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      產品中心您現在的位置:首頁 > 產品展示 > 生化與分子 > 小分子化合物 > Aconitine

      Aconitine

      更新時間:2022-01-28

      簡要描述:

      A lipid-soluble neurotoxin that acts as a sodium channel modulator. Binds with high affinity to the open state of the voltage-sensitive sodium channels at site 2, thereby causing a persistent ……

      型號:廠商性質:代理商瀏覽量:992
      A lipid-soluble neurotoxin that acts as a sodium channel modulator. Binds with high affinity to the open state of the voltage-sensitive sodium channels at site 2, thereby causing a persistent activation of the sodium channels, which become refractory to excitation.


      Product Details

      Alternative Name:(1α,3α,6α,14α,15α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-acetate 14-benzoate

      Formula:C34H47NO11

      MW:645.7

      Source:Isolated from Aconitum karacolium.

      CAS:302-27-2

      MI:14: 118

      RTECS:AR5960000

      Purity:≥98% (HPLC)

      Appearance:White to off-white powder.

      Solubility:Soluble in 100% ethanol (35mg/ml); almost insoluble in water (0.3mg/ml).

      Shipping:Ambient

      Long Term Storage:+4°C

      Handling:Protect from light.

      Regulatory Status:RUO - Research Use Only

      ALX-550-232
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      ALX-550-232


      Product Literature References

      Non-quantal acetylcholine release at mouse neuromuscular junction: effects of elevated quantal release and aconitine: S.P. Yu & W. Van der Kloot; Neurosci. Lett. 117, 111 (1990), Abstract;
      Synthesis and activity of a potent N-methyl-D-aspartic acid agonist, trans-1-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acids: M. Muroi, et al.; Neuropharmacology 29, 567 (1990), Abstract;


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