Altas Antibodies熱銷抗體介紹：Anti-ATRX Antibody

X連鎖α-地中海貧血／精神發育遲滯（又叫ATR-X綜合征）是一種X連鎖遺傳的精神發育遲滯綜合征。大約有一半的患者已發現有ATRX基因突變。轉錄調節因子ATRX也稱為ATP依賴性解旋酶ATRX。X連鎖核蛋白（XNP）或X連鎖解旋酶II是由ATRX編碼的蛋白質。ATRX基因的突變與X連鎖精神發育遲滯（XLMR）綜合征相關，常伴有α-地中海貧血（ATRX）綜合征。

產品詳情：

類型：多克隆抗體

來源：Rabbit IgG

應用： IHC,WB,ICC-IF

反應種屬：human

免疫原：Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQ-QLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQ-QMLISCVQRILMNRR

緩沖液組成：40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative

應用實例：

Immunohistochemical staining of human uterine cervix shows moderate to strong nuclear positivity in sequamous epithelial cells.

WB analysis in A549 cells transfected with control siRNA, target specific siRNA probe#1 and #2, using anti-ATRX antibody. Remaining relative intensity is presented. Loading control:anti-GAPDH.

Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm and nuclear bodies. Antibody staining is shown in green.

訂購信息：

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